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Entelligence Young Investigator Program

Grants to USA and Canada Researchers for Projects
in the Field of Cardiopulmonary Medicine

Agency Type:

Foundation / Corporation

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Entelligence - Actelion Pharmaceuticals US

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Grants to USA and Canada researchers affiliated with qualified institutions for projects in the field of cardiopulmonary medicine. Applicants must submit an LOI prior to submitting a full proposal. Funding is intended for research to reach a better understanding of an approach to disorders of pulmonary vascular biology, particularly pulmonary hypertension.

ENTELLIGENCE is a program designed for basic science, translational and clinical research in the field of cardiopulmonary medicine. The ENTELLIGENCE program provides opportunities for individual young investigators to promote quality medical care and enhance patients' lives by supporting research (basic science, translational and clinical research) in the area of pulmonary hypertension (PH) related to expanding knowledge of the pathways involved in pulmonary vascular pathobiology and ultimately, to improve treatment for patients with pulmonary hypertension.

These grants are awarded by the ENTELLIGENCE Steering Committee to qualified investigators who show promise in their investigations and are based on scientific merit, originality, feasibility, and applicability to the diagnosis and treatment of PH. A condition of the grant application and funding is supervision by an appropriate mentor.

Applications will be considered for basic science, translation, or clinical research specifically targeting pulmonary vascular disease including, but not limited to, the following areas:

  • Pathophysiology
  • Pharmacology
  • Treatment
  • Genetics
  • Diagnosis
  • Epidemiology

GrantWatch ID#:

GrantWatch ID#: 192998

Estimated Size of Grant:

Every project awarded will receive up to $100,000.

Term of Contract:

Research should commence no later than 6 months after approval of the grant, unless an alternative date for commencement has been approved by the Steering Committee. Funded projects should be completed within 12 months of commencement. Clinical follow-up after the 12-month limit is allowed, however, if properly justified by the applicant and corroborated by the outcomes and data delivered. Special consideration will be given by the Steering Committee to allow an additional period of time (maximum 12 months) to conduct research, but not to supply additional funding.

Additional Eligibility Criteria:

Criteria for eligible applicants:
1. Applicants must be a United States (US) citizen, a permanent US resident, a Canadian citizen, or permanent Canadian resident at time of LOI submission. Applicants with nonimmigrant visas are not eligible to apply.
2. Applicants must be engaged principally in basic science, translation and/or clinical research, with a proposal aimed at understanding the pathways and pathophysiology of pulmonary vascular disease.
3. Applicants must have no more than 5 years of experience beyond his/her first faculty appointment at the start of the award (as of July 1st of the award year). [Prior appointments in a different area of research will require an explanation in the application, to avoid being counted as part of the “5 years of experience” criteria.]
4. Significant funding from any of the following grants or awards will disqualify the applicant: US: NIH-R01, NIH-P01 project, VA Merit Review Award, NSF, DOD or equivalent, NIH-K awards, AHA-SDG, NSA Career Development Award, VA Career Development Award or equivalent. Canada: CIHR (Project grant), Heart and Stroke Foundation Grant (National Award)
5. Applicants must have completed their primary research training (PhD or sub-specialty fellowship training) by July 1st of award year. Applicants can be a junior faculty member (up to and including the rank of Assistant Professor), postdoctoral scholar, doctoral candidate or fellow (last year and finishing by July 1st of the award year).
6. Applicants must have a firm commitment from their home institution for mentored career development. (The applicant’s mentor should be involved in overseeing the means for adequate funding to support necessary research, ensuring protected time for the applicant to complete his/her research and to investigate career development, and helping the applicant obtain a firm commitment from the applicant’s institution. This must be carefully addressed in the mentor's letter).
7. Applicants may not be an employee of a commercial entity (eg, pharmaceutical company).

For items ineligible for funding, see

Pre-Application Information:

- LOI Submission: Jan 4 - March 1, 2021
- LOI Review: March 8 - 22
- Grant Submission: April 5 - May 19
- LOI Selection Call: March 29
- Grant Review: May 24 - June 7
- Selection Meeting: June 14
- Notify Applicants: June 28

Initially, a Letter of Intent (LOI) is required for consideration of a proposal. If the LOI is accepted, an invitation to submit a full proposal is then requested.

New award winners must attend the ENTELLIGENCE Award Ceremony held at the annual ATS meeting in May of the year the award is to begin; travel and one-night hotel stay will be provided. Mentors are encouraged to attend; their travel and one-night hotel stay will also be provided.

Applicants may submit only one ENTELLIGENCE research proposal per application round. Past winners will not be allowed to submit another LOI during the subsequent award cycle.

Application Forms:
LOI Submission Process:
Guidelines for Grant Submission:

Contact Information:

Before starting your grant application, please review the funding source's website listed below for updates/changes/addendums/conferences/LOIs.

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URL for Full Text (RFP):

Geographic Focus:

USA: Alabama;   Alaska;   Arizona;   Arkansas;   California;   Colorado;   Connecticut;   Delaware;   Florida;   Georgia;   Hawaii;   Idaho;   Illinois;   Indiana;   Iowa;   Kansas;   Kentucky;   Louisiana;   Maine;   Maryland;   Massachusetts;   Michigan;   Minnesota;   Mississippi;   Missouri;   Montana;   Nebraska;   Nevada;   New Hampshire;   New Jersey;   New Mexico;   New York City;   New York;   North Carolina;   North Dakota;   Ohio;   Oklahoma;   Oregon;   Pennsylvania;   Rhode Island;   South Carolina;   South Dakota;   Tennessee;   Texas;   Utah;   Vermont;   Virginia;   Washington, DC;   Washington;   West Virginia;   Wisconsin;   Wyoming

Canada: Alberta;   British Columbia;   Manitoba;   New Brunswick;   Newfoundland and Labrador;   Northwest Territories;   Nova Scotia;   Nunavut;   Ontario;   Prince Edward Island;   Quebec;   Saskatchewan;   Yukon;

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